The importance of metal geometry in the recognition of G-quadruplex-DNA by metal-terpyridine complexes.
نویسندگان
چکیده
A family of terpyridine metallo-organic complexes has been designed and its recognition properties of G-quadruplex-DNA investigated. The series combines easy synthetic access and good affinity-selectivity ratio for quadruplex-DNA. Our study also highlights that the geometry of the metal center strongly governs the ability of the compounds to discriminate quadruplex from duplex-DNA.
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ورودعنوان ژورنال:
- Organic & biomolecular chemistry
دوره 5 16 شماره
صفحات -
تاریخ انتشار 2007